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TNF- triggers hepatocyte apoptosis, necrosis, liver inflammation and regeneration, autoimmune hepatitis and HCC, making it a promising diagnostic biomarker and appealing therapeutic target for NAFLD-associated HCC (135) demonstrated that TNF- inducible gene 6 protein and its derived peptide could ameliorate the liver fibrosis in mice with ALD by restraining CD44 activation, so as to be a treatment approach for ALF

PMID: 33603376

The form for the fourth term was chosen because the data in [27] indicate that at normal cysteine concentrations (approximately 200 M) most of the flux away from cysteine is toward GSH and only a moderate amount towards other pathways