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Abnormal ECG Anaphylactic and anaphylactoid reactions including hypotension Neuroleptic malignant syndrome (NMS) a potentially fatal side effect of antidopaminergic agents such as antipsychotics, tricyclic antidepressants and antiemetics (drugs that relieve nausea and vomiting)

Vitamin A or its derivatives bind to radicals of oxygen, thiol, or peroxide, limiting their oxidative damage on cells

reported that CB-839 could promote the production of reactive oxygen species (ROS) in colorectal cancer cells, cause nuclear translocation of Nrf2, and subsequently upregulate the expression of uridine phosphorylase 1 (UPP1), which promotes the activation of 5-fluorouracil (5-FU)

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