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Omega-3 and omega-6 PUFA are incorporated into phospholipids, where they not only serve structural roles in cell membranes of the nervous system, but also affect membrane fluidity, flexibility, permeability, as well as the activities of membrane-associated enzymes and receptors (13, 90)

Unraveling mucin domains in cancer and metastasis: When protectors become predators

Biomaterials 94B, 372379

Similarly, iridium (III) complexes trigger ferroptosis and autophagy in A549 cells through GSH depletion, MDA/LPO elevation, GPX4/ferritin downregulation, and BECN1-mediated ferritinophagy-all in an HMGB1-dependent manner ( Lung adenocarcinoma (LUAD), the most prevalent NSCLC subtype, often develops resistance to epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance and exhibits low immune checkpoint expression