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Pharmacol Res 1(163):105254 Cecon E, Chen M, Marola M, Fernandes PA, Jockers R, Markus RP (2015) Amyloid peptide directly impairs pineal gland melatonin synthesis and melatonin receptor signaling through the ERK pathway

The underlying mechanism involves methanogenic archaea converting hydrogen into methane, thereby allowing for greater energy extraction from the same daily caloric intake (151154)