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The WADA and USADA have banned this substance in sports, namely due to the risks it poses to humans considering there is insufficient research

While ( S )- 48 is a product of kinetic resolution, the formation of (2 R ,3 R )- 50 results from the intramolecular opening of the oxirane ring in (3 R ,4 S )- 49

doi: 10.1093/neuonc/nop068

When the bodys defenses are weakened, pathogenic bacteria usually transmit through the respiratory system, penetrate the lung barrier and cause infections (Yu et al., 2023