oral vs injection b12 Vitamin B-12 Injections Pills: Expert Insights Oral vitamin B12 versus intramuscular

Many questions regarding vitamin B12 form, dosage, administration route, and duration of treatment require clarification

Maintenance doses are typically 1 mg every 2-3 months for life High-dose oral therapy (1000-2000 micrograms daily) may be effective in selected patients with pernicious anaemia under clinical supervision, as passive diffusion can compensate for absent intrinsic factor, though this is not routine first-line treatment in the UK The water-soluble nature of B12 means that high-dose supplementation carries minimal risk of toxicity , making it a safe option for individuals with confirmed or suspected deficiency

At the humoral level, both IgG and secretory dimeric IgA (sIg) may be present in the airway mucosa

Specific tests to help diagnose vitamin B12 deficiency are: Getting more vitamin B12 treats the deficiency