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And lipid peroxidation accumulation is one of the characteristics of ferroptosis, so we speculate that ferroptosis plays an essential role in the initiation and development of atherosclerosis

doi: 10.1158/1535-7163.MCT-15-0501 100 ZouGZhangXWangLLiXXieTZhaoJet al

doi: 10.3390/ijms21010300 35 FaasMMDe VosP

CYP1A1 and CYP1B1 metabolize environmental polycyclic aromatic hydrocarbons (PAHs) and other xenobiotics alongside estrogens, generating reactive metabolites that GSTM1 and GSTT1 must also process