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doi:10.3390/ijms18102157 267

In contrast, D-lactate has been observed to promote histone deacetylase (HDAC) protein gene expression, potentially serving as a crucial transcriptional regulator (132, 133)

The healthier metabolic state was defined by higher glucose metabolism substrate levels and corresponded to higher levels of ketogenic AAs/BCAA metabolite derivatives (tyrosine, threonine, valine, 4-methyl-2-oxovaleric acid and propionylcarnitine), ketone bodies (3-hydroxybutyrate and 2-hydroxybutyrate), and butyrylcarnitine (a metabolite involved in fatty acid metabolism

The improvements at the head of the pipeline increased the available supply of water by 3 million gallons a day, from 21 to 24 million gallons a day, which constituted a comfortable surplus beyond the current demand