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Antonioni A, Raho EM, Lopriore P, Pace AP, Latino RR, Assogna M, Mancuso M, Gragnaniello D, Granieri E, Pugliatti M, et al

Clinical challenges and mitigation strategies Core clinical and research challenges With the widespread clinical use of platinum-based chemotherapeutics, long-term in vivo platinum accumulation has emerged as a critical yet underrecognized clinical challenge, serving as the core toxicological driver of impaired long-term quality of life and adverse health outcomes in cancer survivors

Discussion Our findings suggest a potential association between GSTM1 and GSTT1 deletion polymorphisms and the development of MM

Notably, disorganized communication, impoverished language and thought processes related to verbal memory, and motor impoverishment overlapping with working memory were particularly linked 55