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243 The overexpression of VDR signaling can also maintain intestinal epithelial homeostasis and intestinal barrier function by upregulating claudin-2 and claudin-15

Addressing these underlying factors is important for optimal management and may involve treatments targeting the primary disease in addition to symptom control

This helps reduce inflammation and supports the high energy demands of cellular repair, creating a more favorable environment for the newly introduced stem cells

There were no statistically significant differences in one- and two-year overall survival between groups, suggesting the high-dose antioxidants did not reduce the efficacy of chemotherapy (Pathak 2005)