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In the acute window (024 h) the priority is to contain ROS spikes (e.g., ischemiareperfusion, SIRS) by attenuating the source (NOX/mitochondrial bursts), buffering at the compartment of origin (mitochondria, ER, endothelium) and controlling free metals that license Fenton chemistry

Hydrops fetalis are categorized as immune and non-immune, the latter referred to as NIHF