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This shift is potentially advantageous for endurance athletes, as it suggests a preservation of muscle glycogen stores during exercise

Biochem J 398:107112 Schwagerl AL, Mohan PS, Cataldo AM, Vonsattel JP, Kowall NW, Nixon RA (1995) Elevated levels of the endosomal-lysosomal proteinase cathepsin D in cerebrospinal fluid in Alzheimer disease