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As seen in Supplemental Figure 4B, the sum of total intracellular hydroperoxy- and hydroxy-phospholipids following IL-13 stimulation was approximately 2 nmol/mg protein, that is, sufficient amounts to quantifiably impact the change in intracellular GSH (and the increases in GSSG) under these two conditions, as shown in Supplemental Figure 4C under similar conditions

Furthermore, calcium and metal ion homeostasis are closely linked to mitochondrial function [189]

doi: 10.1523/JNEUROSCI.0232-09.2009 235 NavarreteM.AraqueA

The anti-inflammatory mechanisms are primarily mediated through the inhibition of the NF-B signaling cascade