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J Sex Med (2018) 15(8):107382

The single clinical trial that was initiated was canceled

Efficacy of osimertinib plus bevacizumab in glioblastoma patients with simultaneous EGFR amplification and EGFRvIII mutation

Interestingly, although CD8 + T cell activation induced by ferroptosis can kill tumor cells by releasing IFN- [17], the presence of IFN- simultaneously leads to upregulation of PD-L1, which induces adaptive immune resistance and T cell dysfunction [79,80,81]