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In vitro, NRF2 overexpression in murine HCC cells activated the COX2/PGE2/EP4 pathway and upregulated TGF and VEGF-A

The expanding incretin universe: from basic biology to clinical translation

2A and B) further confirmed the enhanced cellular uptake of CUR/miR155@DssD-Hb NPs in B16F10 and 4T1 cells facilitated by the ROS- and GSH-sensitive groups, exhibiting a 1.53- and 1.33-fold increase in cellular uptake compared to Cy5-miRNA@Lipo at 4 h