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A single 30 g dose of gluten caused a transient increase in cellobiose excretion in well-controlled patients with normalization within 1 week ( The barrier defect in CeD is hypothesized to contribute to diarrhea by a paracellular flux of water and solutes ( Two decades ago, increased zonulin protein concentration was shown in patients with active CeD by the group of Fasano ( ex vivo in biopsies of healthy volunteers and patients with quiescent CeD ( Comparison of the amino-terminal end of zonulin and the active fragment of Zot (98), corresponding to the amino acids 815 of this fragment, did not affect permeability, but pretreatment offered significant protection against the effect of subsequent treatment with purified Zot or zonulin (98)

doi: 10.5306/wjco.v8.i2.120

The results indicate a significant decrease in reintubation rates, in incidence of atelectasis, and in mortality for patients treated with the regimen of heparin and N-acetylcystine [corrected] when compared with controls

Place-based environmental civic science projects enable students to apply STEM knowledge to local issues, fostering perceptions of relevance and community impact [49]