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It was also difficult to compare interventions because the types of supplements, the dosages taken, and the length of time they were taken varied widely

Tsai-Turton & Lauderer in their publication in the journal Endocrinology reported that evidence proves oxidative stress (inflammation) induces apoptosis (cell death) in preovulatory follicles and that the antiapoptotic (preventing cell death) effect of FSH is mediated in part by stimulation of follicular glutathione (GSH) and suppression of ROS production

Fernndez-ChecaJCKaplowitzNGarca-RuizCColellAMirandaMMarMet alGSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect