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Autism is also associated with increased mast cell activation, which plays a central role in driving allergic reactions

In ERS state, HSPs may participate in the process of apoptosis through Fas/caspase8 pathway and be exposed on the cell membrane (111), while HSPs may be passively released into extracellular matrix during cell death

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11.1.2 Calcium and vitamin D supplementation is recommended to prevent and treat osteopenia/osteoporosis in children on long-term steroid therapy (LOE 4, Strong recommendation)