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G., Linear mass scans in quadrupole ion traps using the inverse Mathieu q scan

This technique reveals how the binding of one component induces conformational changes in the target protein that enhance the binding of a second component (through "conformational selection") or stabilize specific functional states, thereby quantifying allosteric communication between binding sites

Investigators have studied the compound in combination with other research molecules, in biomaterial-integrated delivery formats, and in cell-type-specific contexts that broaden the mechanism understanding documented in foundational papers