most common place for melanotic macule Lingual – the first case report in an adult patient* Differential Diagnosis of Pigmented Lesions

Physiological melanin hyperpigmentation does not require treatment, but if for cosmetic reasons it has to be removed, laser or cryotherapy or surgical excision are often successful

Patients might also use simpler diaries or logs of sexual activity noting each attempt at intercourse, whether penetration was successful, and whether the erection was maintained to climax (these correspond to the Sexual Encounter Profile (SEP) questions often used in ED studies)

Some authors propose that the relatively large size of most atypical naevi may be due to longer telomeres, leading to decreased cellular senescence

La melanina se produce en los melanocitos, una poblacin especializada de clulas dendrticas que ocupa normalmente la regin de clulas basales del epitelio plano en la piel y las mucosas