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408 Within this complex interplay of diet, metabolism, and inflammation, IL-17 has been identified as a key player in metabolic dysregulation associated with HFD, where inhibiting IL-17A production or blocking its receptor can attenuate obesity by enhancing adipose tissue browning and energy dissipation

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doi: 10.1172/JCI153283 123 FernndezVSalameroOEspinetBSolFRoyoCNavarroAet al