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Specifically, Thomas et al (2018) made their measurements 4 weeks after the nicotine treatment, and they did not observe nicotine-induced dysfunction of VTA GABA transmission in adult rats when measured at 4 weeks after nicotine exposure in adulthood (see Fig 2 in Thomas et al., 2018)

Stem Material: Acrylic Filter: None Shape: Freehand Finish: Rusticated Material: Briar Country of Origin: Denmark Each pipe is individually photographed in-house unless otherwise noted

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However, there is an acknowledgment from experts that these pop-culture depictions are a cause for concern