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Subsequent RNA-seq analyses corroborated the activation of oxidative-stress and mitochondrial-dysfunction pathways, indicating that the parasite re-programmes host metabolism and stress responses to support its own development (Tamez et al., 2011), a cytokine known to suppress hepcidin and thereby exacerbate ineffective erythropoiesis (Tanno et al., 2007

eLife 9:e59711

Nitric Oxide Reacts with Intracellular Glutathione and Activates the Hexose Monophosphate Shunt in Human Neutrophils: Evidence for S-Nitrosoglutathione as a Bioactive Intermediary