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An integrated gene catalog and over 10,000 metagenome-assembled genomes from the gastrointestinal microbiome of ruminants

In addition, plateau pulmonary hypertension and increased pulmonary blood flow resistance will also lead to increased right heart load and right ventricular myocardial hypertrophy, ultimately leading to irreversible damage to the myocardium and cardiac conduction system [74, 76]

In summary, our research has revealed a novel mechanism in which gankyrin increases the expression of SLC7A11 and GPX4 through p53 ubiquitination, thus hindering ferroptosis-induced cell death in TNBC and potentially facilitating cancer cell survival

Geographically, Latin America and the Caribbean had the highest proportion of DR-related blindness (6.9%), whereas North Africa and the Middle East reported the highest rates of MSVI (2.1%)