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Figure 4 Intracellular GSH Is a Regulator of BDG-Induced NADP Synthesis and Pentose Phosphate Pathway Metabolism To determine the role of the GSH induction by BDG on monocyte function, we evaluated the impact of blocking GSH synthesis using L-buthionine sulfoximine (BSO), an inhibitor of -glutamylcysteine synthetase (GCLC) (38)