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see Vitamin B12 Health Professional Fact Sheet

Increasing your intake of vitamin-B-rich foods and/or supplementing with these B vitamins has the potential to improve nerve function and repair, leading to pain relief, reduced inflammation, and nerve tissue regeneration

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The solution here was vaginal administration of THC (the active component of marijuana) to the mice (how would you like that job :-).[ref] Mast cells and rheumatoid arthritis: Rheumatoid arthritis is an autoimmune disease that causes painful inflammation of the joints