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This copper-mediated Fenton-like chemistry can inflict extensive cellular damage, including DNA strand breaks, protein oxidation and denaturation, lipid peroxidation, and ultimately cell death (Adlard and Bush 2006

Guidelines further recommend follow-up after at least 6 weeks to check the effectiveness of treatment and potential change of BP medication regime by adding other BP medication classes, increasing dosage, or changing BP medication type, depending also on tolerability and potential side effects

These should only be performed by a trained professional

(2018) [192] also show that early-life stress causes long-term decreased PV expression and density of PV neurons in orbitofrontal cortex which result in impaired rule-reversal learning