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Whole blood, its components (plasma or serum) and circulating cells (peripheral blood lymphocytes, circulating neutrophils, freshly isolated monocytes, red blood cells) are frequently studied in the field of oxidative stress research (Regelmann et al., 1991

doi: 10.7759/cureus.10405 Brian Patterson, Sophia Sangar, Raja Gnanadev, George Makkar, Michael Neeki

Artery occlusion decreases H3K4me3 levels in astrocytes

In other words, the combined treatment revealed a stronger inhibitory effect on cyclin D1 expression, causing cell cycle arrest, than each treatment alone