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Sarkar S, Chauhan S, Daly J, Natoni A, Fairfield H, Henderson R

Spontaneous glutamatergic activity induces a BDNF-dependent potentiation of GABAergic synapses in the newborn rat hippocampus

In the Phase II ZUPREME-1 trial, petrelintide monotherapy produced placebo-adjusted weight loss of up to 9% at 42 weeks, putting it closer to cagrilintide monotherapy from Novo Nordisk A/S (CSE:NOVO-B