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be present in the to use by oneself enrichment of the SK-MEL-28 cell that Q10 in the culture medium of 100uM handles The HPLC-MS quantitative result of the level of the Q10 in the mitochondrial sample Surprising result from this research finds that Q10 offers cell with oxidised form.For 48 hours sample, also measure reduction form Q10H2, and find that it exists with significantly lower amount (the 0.28ng/ sample of CoQ10H2 is with respect to the 46.63ng/ sample of CoQ10).In 48 hours sample of Q10 processing, there is the overall increase (3 times) of the level of Q10H2, though the mensuration detectability of the said supposition of being on close level.Enjoyably, oxidised form (Q10) can be used as the prooxidant in the biosystem.According to document, as the Q10 that estimates human plasma during with Q10H2, find major part (90%) molecule with the reduction form Q10H2 that can be used as antioxidant exist (Ruiz-Jimenez, 2007, J.Chroma A, 1175,242-248)