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In nutraceuticals, these problems afflict even the most well-meaning protocols

Notably, we previously showed that administering Tempol (a potent ROS scavenger) or genetically deleting Ncf1 (which impairs the respiratory burst) led to bacterial outgrowth in mice 7

Spontaneously formed methemoglobin is normally reduced (regenerating normal hemoglobin) by protective enzyme systems, e.g., NADH methemoglobin reductase (cytochrome-b5 reductase) (major pathway), NADPH methemoglobin reductase (minor pathway) and to a lesser extent the ascorbic acid and glutathione enzyme systems

These compounds can serve as the potential biomarkers of lipid peroxidation [5, 35]