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10.1038/ncomms6845 Nat

When Deura utilized IL-6 to culture granulosa tumor cell lines, it could enhance ERK1/2 phosphorylation, limit CYP19 expression, and diminish estrogen release (89)

Wiley Online Library 27 SangweniNFGabuzaKHuisamenBMabasaLvan VuurenDJohnsonR

When combined with capecitabine, QUE increased the killing effect of capecitabine on COLO320 CRC cells and MCF-7 BC cells, and arrested the cell cycle by inducing mitochondrial depolarization and promoting the expression of Caspase-3, while it had no cytotoxicity on normal mouse fibroblast 3T3-L1 cells (38)