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[19] Pernicious anemia [edit] Pernicious anemia is a disease caused by an autoimmune response that produces antibodies that attack the parietal cells in the stomach lining, preventing them from creating intrinsic factor needed for the absorption of vitamin B 12

Long-term use of proton-pump inhibitors has been found to decrease blood vitamin B 12 concentrations

The timing of the vitamin B12 laboratory test varied from 2 months to 4 months before the first intramuscular injection

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