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Nadal R, Mortazavi A, Stein MN, Pal SK, Lee DK, Parnes HL, et al

It was originally isolated from human gastric juice, where it appears to play protective roles in the digestive tract

Furthermore, experimental OECD TG471-compliant mutagenicity testing requires NA-specific adaptation of the standard protocols (Organisation for Economic Co-operation and Development 2020), as the sensitivity of the standard OECD TG471 Ames test has been questioned for NAs by regulatory agencies (European Medicines Agency 2025