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Thus, vitamins were not prescribed to such patients

doi: 10.21272/eumj.2023;11(1):1-13 45

It can be classified into different subtypes based on pathology, including clear cell carcinoma, chromophobe carcinoma, renal papillary cell carcinoma, medullary carcinoma, and undifferentiated carcinoma (233)

It is also evident that many of the antioxidant enzymes are induced by GSH depletion at the transcriptional level which involves the binding of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor to the antioxidant response element (ARE) in the promoter region of the genes encoding GCL and glutathione S -transferases [16]