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doi: 10.1016/j.celrep.2019.06.071 178

(2021) speculated that the downregulated genes involved to amino acid synthesis pathways could be due to the presence of high levels of NaCl

Given a satisfactory safety profile, a phase Ib trial was recently conducted in psoriasis patients with results yet to be published (NCT02435342) (Table 2)

P53 inhibits cystine uptake and sensitizes cells to ferroptosis by inhibiting the expression of SLC7A11, a key component of cystine/glutamate retrotransporters