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Laser Doppler Flowmetry Gingival blood flow (GBF) was measured by laser doppler flowmetry (LDF, Oxford Optronix Ltd, Oxford, UK) working at 780 nm

The identified reactions in both the scenarios can be linked to important immune responses and have been linked to signaling pathways involved in macrophage polarization 55

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In mammalian tissues, they also serve as scavengers of oxygen free radicals, effectively preventing oxidative stress-induced mitochondrial damage and mitochondria-dependent apoptosis in a variety of cell types 32,33,34