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Bourgoin, Laval University, Canada Arijit Chakraborty, Massachusetts General Hospital and Harvard Medical School, United States Updates Copyright 2026 Hao, Klein, McBride, Bohannon, Patil, Davis, Oliver, Dye, Weidenbach, Young and Sherwood

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Ethanol has been shown to increase the expression of TNF- and FasL in the brain, thereby enhancing the activation of the extrinsic apoptotic pathway

Similarly, there is abnormal activation of neutrophils in diabetic patients, which damages tissues and organs by yielding increased amounts of ROS and pro-inflammatory cytokines (140, 141)