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Also our data confirmed the anti-inflammatory and antioxidant properties of vitamin c as the UTI + C, and UTI + N + C groups showed significant decreases in the inflammatory mediators (MDA, and NFkB) but increases in antioxidants (GSH, and TAC) compared to the UTI group

These results strongly suggest that Ubx employs distinct molecular mechanisms to regulate exclusively spliced genes ( Pura ) compared to the gene regulated at both transcription and splicing levels ( Chas )

Overall, this data suggests that these four efflux pumps of different families are all involved in the rescue of the cells from 5-OP toxicity

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