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Thats because peptides can easily break down in the digestive tract and are often too molecularly large to permeate the intestinal wall.20 Oral alternatives may use technologies like protective capsules and permeability agents to bypass these obstacles, but injection remains the most common peptide delivery method.20 Collagen peptides are an exception

Subsequently, RVG peptide-guided exosomes were employed to deliver short interfering RNA to neurons, microglia, and oligodendrocytes in the brain by targeting the gamma-aminobutyric acid (GABA) receptor, inducing target gene knockdown with negligible nonspecific uptake in other tissues 35

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