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the presence of at least one G allele causing an anticipated disease onset of 5.4 years 65

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Mo- lybdenum is an essential cofactor in several Wilsons disease is a rare inherited disorder enzyme systems that are important for meta- of copper storage (affecting 1 in 200 000 bolism, detoxification, and excretion of poten- people), in which biliary excretion of copper tially harmful compounds.1,2 is impaired.12 This results in accumulation of copper in the liver and brain that can lead Functions to cirrhosis, liver failure, and neurologic damage