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SCFAs, particularly butyrate, are known to support epithelial and BBB integrity and regulate microglial homeostasis, whereas altered microbial composition in PD may shift metabolite profiles toward a more pro-inflammatory state [123]

(113) provided evidence for a small molecule inhibitor, N3 (a benzothiazole derivative) to arrest tau aggregate formation in sea lamprey neurons (113)

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Martemucci, G., Costagliola, C., Mariano, M., Dandrea, L., Napolitano, P., and DAlessandro, A.G., Oxygen , 2022, vol