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Patients should be reviewed 812 weeks after commencing treatment to assess: Symptomatic improvement, particularly resolution of fatigue and neurological symptoms Haematological response (normalisation of haemoglobin and mean cell volume) Reticulocyte count typically rises within one week, indicating bone marrow response Repeat serum B12 testing is generally not useful after starting parenteral therapy, as levels remain elevated for months

However, long-term safety data is limited, and its full risk profile is not yet completely understood

Hence, its always great to see physicians worldwide testing autologous biologics, like platelet rich plasma, against steroids for SI joint pain

J., & Auwerx, J