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There is also a rule that matters for anyone in competitive sport, since AOD 9604 is prohibited by the World Anti-Doping Agency, so athletes subject to testing need to be aware before they consider it

David Sinclair, a leading voice in longevity research, has stated: NAD+ is the closest we've gotten to a fountain of youth.[2] His research highlights how NAD+ activates pathways that mimic caloric restriction, a known extender of lifespan in models

Studies and anecdotal reports highlight: Increased lipolysis (breakdown of fat cells) Improved body composition No significant increase in IGF-1 or growth-related side effects However, results are often modest compared to aggressive weight-loss drugs