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This process can involve gut microbiota metabolites crossing the blood-brain barrier, modulating the microbiota-gut-brain axis, and regulating microglial activity and cytokine release

When introduced into living organisms, such as mouse model, siRNA/Ap-CS nanostructures can reach specific tissues and organs by the blood circulation system and enter into target cancer cells by aptamerreceptor interaction without the need of transfection reagents (step IV)

Research Focus Researchers use AOD-9604 to study peptidereceptor interactions, metabolic signaling pathways, and biochemical processes associated with GH-derived peptide fragments

Ozdemir BC, Pentcheva-Hoang T