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ORiordan KJ, Moloney GM, Keane L, Clarke G, Cryan JF

10.1016/S0006-2952(03)00504-5 52

Insufficient sleep can cause increased cytokine secretion provoking an inflammatory response in various tissues including the brain which is associated with cognitive impairment [2]

Schedule (Once Weekly Injection) Upper limit: 12 mg per week is the highest dose used in the major published clinical trials (Phase 2 obesity, Phase 2 type 2 diabetes, and the Phase 3 TRIUMPH-4 and TRANSCEND-T2D-1 studies)