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Krasnyi and colleagues also evaluated the methylation status of a panel of four genes, including glial cells missing homolog 2 ( GCM2 ) , inositol 1,4,5-trisphosphate receptor-interacting protein like 1 ( ITPRIPL1 ) , calcium voltage-gated channel subunit alpha1 E ( CACNA1E ), and discs large homolog-associated protein 2 ( DLGAP2 ), in a cohort of BRCA patients ( N = 96) and controls ( N = 24 fibroadenoma tissue samples and 24 healthy tissue samples) [133]