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However, further large-scale, well-controlled studies are needed to confirm its efficacy and to determine optimal dosing strategies

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For mitochondrial glutaminolysis, cytosolic glutamine must be transported through the inner mitochondrial membrane via the SLC1A5 variant, a mitochondrial glutamine transporter 16

Xu W, Yan J, Ocak U et al (2021) Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK/SIRT1/PGC-1 pathway in rats