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Additionally, single domain antibodies called nanobodies might be an alternative to scFvs (Hamers-Casterman et al., 1993)

It also explains why ignoring these risk factors may lead to serious complications

Establishment of a Physical Association Between Polypeptides and Their Genetic Material A basic concept of display methods that use phage or other replicable genetic package is the establishment of a physical association between DNA encoding a polypeptide to be screened and the polypeptide