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Unlike traditional neurotrophic factors, Dihexa crosses the blood-brain barrier efficiently, resulting in improved learning, memory, and recovery in models of neurodegeneration and traumatic brain injury

Neuroplasticity driven by HGF/c-Met signaling includes upregulation of brain-derived neurotrophic factor (BDNF), activation of postsynaptic density protein-95 (PSD-95), and increased expression of GluN2B-containing NMDA receptors

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